Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression

ABSTRACT: Chitinase-3-like 1 protein (CHI3L1) is a secreted glycoprotein, strongly correlated with fibrosis severity in chronic liver diseases including non-alcoholic steatohepatitis (NASH). However, the mechanisms by which CHI3L1 contributes to fibrogenesis remain undefined. Here, we showed that in...

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Detalles Bibliográficos
Autores principales: Kim, Andrea D., Kui, Lin, Kaufmann, Benedikt, Kim, Sung Eun, Leszczynska, Aleksandra, Feldstein, Ariel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300183/
https://www.ncbi.nlm.nih.gov/pubmed/37166517
http://dx.doi.org/10.1007/s00109-023-02325-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300183/
https://www.ncbi.nlm.nih.gov/pubmed/37166517
http://dx.doi.org/10.1007/s00109-023-02325-4

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