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Myeloid-specific deletion of chitinase-3-like 1 protein ameliorates murine diet-induced steatohepatitis progression
ABSTRACT: Chitinase-3-like 1 protein (CHI3L1) is a secreted glycoprotein, strongly correlated with fibrosis severity in chronic liver diseases including non-alcoholic steatohepatitis (NASH). However, the mechanisms by which CHI3L1 contributes to fibrogenesis remain undefined. Here, we showed that in...
Autores principales: | Kim, Andrea D., Kui, Lin, Kaufmann, Benedikt, Kim, Sung Eun, Leszczynska, Aleksandra, Feldstein, Ariel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300183/ https://www.ncbi.nlm.nih.gov/pubmed/37166517 http://dx.doi.org/10.1007/s00109-023-02325-4 |
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