Cargando…

Comparing mechanism-based and machine learning models for predicting the effects of glucose accessibility on tumor cell proliferation

Glucose plays a central role in tumor metabolism and development and is a target for novel therapeutics. To characterize the response of cancer cells to blockade of glucose uptake, we collected time-resolved microscopy data to track the growth of MDA-MB-231 breast cancer cells. We then developed a m...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Jianchen, Virostko, Jack, Liu, Junyan, Jarrett, Angela M., Hormuth, David A., Yankeelov, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300192/
https://www.ncbi.nlm.nih.gov/pubmed/37369672
http://dx.doi.org/10.1038/s41598-023-37238-2