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Comparing mechanism-based and machine learning models for predicting the effects of glucose accessibility on tumor cell proliferation
Glucose plays a central role in tumor metabolism and development and is a target for novel therapeutics. To characterize the response of cancer cells to blockade of glucose uptake, we collected time-resolved microscopy data to track the growth of MDA-MB-231 breast cancer cells. We then developed a m...
Autores principales: | Yang, Jianchen, Virostko, Jack, Liu, Junyan, Jarrett, Angela M., Hormuth, David A., Yankeelov, Thomas E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300192/ https://www.ncbi.nlm.nih.gov/pubmed/37369672 http://dx.doi.org/10.1038/s41598-023-37238-2 |
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