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Globus pallidus internus activity increases during voluntary movement in children with dystonia

The rate model of basal ganglia function predicts that muscle activity in dystonia is due to disinhibition of thalamus resulting from decreased inhibitory input from pallidum. We seek to test this hypothesis in children with dyskinetic cerebral palsy undergoing evaluation for deep brain stimulation...

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Detalles Bibliográficos
Autores principales: Hernandez-Martin, Estefania, Kasiri, Maral, Abe, Sumiko, MacLean, Jennifer, Olaya, Joffre, Liker, Mark, Chu, Jason, Sanger, Terence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300218/
https://www.ncbi.nlm.nih.gov/pubmed/37389183
http://dx.doi.org/10.1016/j.isci.2023.107066