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Intranasal VLP-RBD vaccine adjuvanted with BECC470 confers immunity against Delta SARS-CoV-2 challenge in K18-hACE2-mice

As the COVID-19 pandemic transitions into endemicity, seasonal boosters are a plausible reality across the globe. We hypothesize that intranasal vaccines can provide better protection against asymptomatic infections and more transmissible variants of SARS-CoV-2. To formulate a protective intranasal...

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Detalles Bibliográficos
Autores principales: Lee, Katherine S, Rader, Nathaniel A, Miller, Olivia A, Cooper, Melissa, Wong, Ting Y, Shahrier Amin, Md., Barbier, Mariette, Bevere, Justin R, Ernst, Robert K, Heath Damron, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300285/
https://www.ncbi.nlm.nih.gov/pubmed/37407405
http://dx.doi.org/10.1016/j.vaccine.2023.06.080