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The protective role of Wnt3a in peroxynitrite-induced damage of cochlear hair cells in vitro

OBJECTIVE: To investigate the effect of peroxynitrite on the cultured cochlear hair cells of C57BL/6 P3 mice in vitro as well as the role of Wnt3a, as an activator of the canonical Wnt signaling pathway, underlying the action of such an oxidative stress. METHODS: The in vitro primary cultured cochle...

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Detalles Bibliográficos
Autores principales: Cui, Fengyun, Cao, Zhimin, Zhang, Qianru, Cao, Zhixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300296/
https://www.ncbi.nlm.nih.gov/pubmed/37331234
http://dx.doi.org/10.1016/j.bjorl.2023.101278