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Inhibition of stress proteins TRIB3 and STC2 potentiates sorafenib sensitivity in hepatocellular carcinoma

Sorafenib resistance is one of the main obstacles to the treatment of advanced hepatocellular carcinoma (HCC). Stress proteins TRIB3 and STC2 confer cell resistance to a variety of stresses, including hypoxia, nutritional deprivation, and other perturbations, which induce endoplasmic reticulum stres...

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Detalles Bibliográficos
Autores principales: Zhou, Sheng, Xu, Huanji, Wei, Tianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300369/
https://www.ncbi.nlm.nih.gov/pubmed/37389061
http://dx.doi.org/10.1016/j.heliyon.2023.e17295