Enhancing the effectiveness of γδ T cells by mRNA transfection of chimeric antigen receptors or bispecific T cell engagers

Adoptive cell therapy (ACT) utilizing γδ T cells is becoming a promising option for the treatment of cancer, because it offers an off-the-shelf allogeneic product that is safe, potent, and clinically effective. Approaches to engineer or enhance immune-competent cells for ACT, like expression of chim...

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Detalles Bibliográficos
Autores principales: Becker, Scott A., Petrich, Brian G., Yu, Bing, Knight, Kristopher A., Brown, Harrison C., Raikar, Sunil S., Doering, Christopher B., Spencer, H. Trent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300408/
https://www.ncbi.nlm.nih.gov/pubmed/37387794
http://dx.doi.org/10.1016/j.omto.2023.05.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300408/
https://www.ncbi.nlm.nih.gov/pubmed/37387794
http://dx.doi.org/10.1016/j.omto.2023.05.007

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