Different binding and pathogenic effect of neurofascin and contactin–1 autoantibodies in autoimmune nodopathies

INTRODUCTION: IgG4 autoantibodies against paranodal proteins are known to induce acute-onset and often severe sensorimotor autoimmune neuropathies. How autoantibodies reach their antigens at the paranode in spite of the myelin barrier is still unclear. METHODS: We performed in vitro incubation exper...

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Detalles Bibliográficos
Autores principales: Hecker, Katharina, Grüner, Julia, Hartmannsberger, Beate, Appeltshauser, Luise, Villmann, Carmen, Sommer, Claudia, Doppler, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300411/
https://www.ncbi.nlm.nih.gov/pubmed/37388725
http://dx.doi.org/10.3389/fimmu.2023.1189734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300411/
https://www.ncbi.nlm.nih.gov/pubmed/37388725
http://dx.doi.org/10.3389/fimmu.2023.1189734

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