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Different binding and pathogenic effect of neurofascin and contactin–1 autoantibodies in autoimmune nodopathies
INTRODUCTION: IgG4 autoantibodies against paranodal proteins are known to induce acute-onset and often severe sensorimotor autoimmune neuropathies. How autoantibodies reach their antigens at the paranode in spite of the myelin barrier is still unclear. METHODS: We performed in vitro incubation exper...
Autores principales: | Hecker, Katharina, Grüner, Julia, Hartmannsberger, Beate, Appeltshauser, Luise, Villmann, Carmen, Sommer, Claudia, Doppler, Kathrin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300411/ https://www.ncbi.nlm.nih.gov/pubmed/37388725 http://dx.doi.org/10.3389/fimmu.2023.1189734 |
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