Effects of acid-sensing ion channel-1A (ASIC1A) on cocaine-induced synaptic adaptations

Chronic drug abuse is thought to induce synaptic changes in nucleus accumbens medium spiny neurons (MSNs) that promote subsequent craving and drug-seeking behavior. Accumulating data suggest acid-sensing ion channels (ASICs) may play a critical role. In drug naïve mice, disrupting the ASIC1A subunit...

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Detalles Bibliográficos
Autores principales: Gupta, Subhash C., Taugher-Hebl, Rebecca J., Hardie, Jason B., Fan, Rong, LaLumiere, Ryan T., Wemmie, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300415/
https://www.ncbi.nlm.nih.gov/pubmed/37389125
http://dx.doi.org/10.3389/fphys.2023.1191275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300415/
https://www.ncbi.nlm.nih.gov/pubmed/37389125
http://dx.doi.org/10.3389/fphys.2023.1191275

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