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Effects of acid-sensing ion channel-1A (ASIC1A) on cocaine-induced synaptic adaptations
Chronic drug abuse is thought to induce synaptic changes in nucleus accumbens medium spiny neurons (MSNs) that promote subsequent craving and drug-seeking behavior. Accumulating data suggest acid-sensing ion channels (ASICs) may play a critical role. In drug naïve mice, disrupting the ASIC1A subunit...
Autores principales: | Gupta, Subhash C., Taugher-Hebl, Rebecca J., Hardie, Jason B., Fan, Rong, LaLumiere, Ryan T., Wemmie, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300415/ https://www.ncbi.nlm.nih.gov/pubmed/37389125 http://dx.doi.org/10.3389/fphys.2023.1191275 |
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