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Phosphorylation mutation impairs the promoting effect of spastin on neurite outgrowth without affecting its microtubule severing ability

Spastin, a microtubule-severing enzyme, is known to be important for neurite outgrowth. However, the role of spastin post-translational modification, particularly its phosphorylation regulation in neuronal outgrowth, remains unclear. This study aimed to investigate the effects of eliminating spastin...

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Detalles Bibliográficos
Autores principales: Zhang, Yunlong, He, Xin, Zou, Jianyu, Yang, Jie, Ma, Ao, Tan, Minghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300427/
https://www.ncbi.nlm.nih.gov/pubmed/36632786
http://dx.doi.org/10.4081/ejh.2023.3594