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Spatially coordinated cell cycle activity and motility govern bifurcation of mammary branches

Branching morphogenesis is an evolutionary solution to maximize epithelial function in a compact organ. It involves successive rounds of branch elongation and branch point formation to generate a tubular network. In all organs, branch points can form by tip splitting, but it is unclear how tip cells...

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Detalles Bibliográficos
Autores principales: Myllymäki, Satu-Marja, Kaczyńska, Beata, Lan, Qiang, Mikkola, Marja L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300433/
https://www.ncbi.nlm.nih.gov/pubmed/37367826
http://dx.doi.org/10.1083/jcb.202209005