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Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics

The patterns of genomic mutations are associated with various genomic features, most notably late replication timing, yet it remains contested which mutation types and signatures relate to DNA replication dynamics and to what extent. Here, we perform high-resolution comparisons of mutational landsca...

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Detalles Bibliográficos
Autores principales: Caballero, Madison, Boos, Dominik, Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300547/
https://www.ncbi.nlm.nih.gov/pubmed/37388911
http://dx.doi.org/10.1016/j.xgen.2023.100315