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Cell-type specificity of the human mutation landscape with respect to DNA replication dynamics
The patterns of genomic mutations are associated with various genomic features, most notably late replication timing, yet it remains contested which mutation types and signatures relate to DNA replication dynamics and to what extent. Here, we perform high-resolution comparisons of mutational landsca...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300547/ https://www.ncbi.nlm.nih.gov/pubmed/37388911 http://dx.doi.org/10.1016/j.xgen.2023.100315 |