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The landscape of somatic mutations in lymphoblastoid cell lines

Somatic mutations have important biological ramifications while exerting substantial rate, type, and genomic location heterogeneity. Yet, their sporadic occurrence makes them difficult to study at scale and across individuals. Lymphoblastoid cell lines (LCLs), a model system for human population and...

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Detalles Bibliográficos
Autores principales: Caballero, Madison, Koren, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300552/
https://www.ncbi.nlm.nih.gov/pubmed/37388907
http://dx.doi.org/10.1016/j.xgen.2023.100305