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Physical inactivity induces insulin resistance in plantaris muscle through protein tyrosine phosphatase 1B activation in mice

Inactivity causes insulin resistance in skeletal muscle and exacerbates various lifestyle-related diseases. We previously found that 24-h hindlimb cast immobilization (HCI) of the predominantly slow-twitch soleus muscle increased intramyocellular diacylglycerol (IMDG) and insulin resistance by activ...

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Detalles Bibliográficos
Autores principales: Kakehi, Saori, Tamura, Yoshifumi, Ikeda, Shin-ichi, Kaga, Naoko, Taka, Hikari, Nishida, Yuya, Kawamori, Ryuzo, Watada, Hirotaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300557/
https://www.ncbi.nlm.nih.gov/pubmed/37389126
http://dx.doi.org/10.3389/fphys.2023.1198390