Sharing parental genomes by siblings concordant or discordant for autism

Studying thousands of families, we find siblings concordant for autism share more of their parental genomes than expected by chance, and discordant siblings share less, consistent with a role of transmission in autism incidence. The excess sharing of the father is highly significant (p value of 0.00...

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Detalles Bibliográficos
Autores principales: Wroten, Mathew, Yoon, Seungtai, Andrews, Peter, Yamrom, Boris, Ronemus, Michael, Buja, Andreas, Krieger, Abba M., Levy, Dan, Ye, Kenny, Wigler, Michael, Iossifov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300587/
https://www.ncbi.nlm.nih.gov/pubmed/37388917
http://dx.doi.org/10.1016/j.xgen.2023.100319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300587/
https://www.ncbi.nlm.nih.gov/pubmed/37388917
http://dx.doi.org/10.1016/j.xgen.2023.100319

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