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Sharing parental genomes by siblings concordant or discordant for autism
Studying thousands of families, we find siblings concordant for autism share more of their parental genomes than expected by chance, and discordant siblings share less, consistent with a role of transmission in autism incidence. The excess sharing of the father is highly significant (p value of 0.00...
Autores principales: | Wroten, Mathew, Yoon, Seungtai, Andrews, Peter, Yamrom, Boris, Ronemus, Michael, Buja, Andreas, Krieger, Abba M., Levy, Dan, Ye, Kenny, Wigler, Michael, Iossifov, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300587/ https://www.ncbi.nlm.nih.gov/pubmed/37388917 http://dx.doi.org/10.1016/j.xgen.2023.100319 |
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