Performance and accuracy evaluation of reference panels for genotype imputation in sub-Saharan African populations

Based on evaluations of imputation performed on a genotype dataset consisting of about 11,000 sub-Saharan African (SSA) participants, we show Trans-Omics for Precision Medicine (TOPMed) and the African Genome Resource (AGR) to be currently the best panels for imputing SSA datasets. We report notable...

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Detalles Bibliográficos
Autores principales: Sengupta, Dhriti, Botha, Gerrit, Meintjes, Ayton, Mbiyavanga, Mamana, Hazelhurst, Scott, Mulder, Nicola, Ramsay, Michèle, Choudhury, Ananyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300601/
https://www.ncbi.nlm.nih.gov/pubmed/37388906
http://dx.doi.org/10.1016/j.xgen.2023.100332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300601/
https://www.ncbi.nlm.nih.gov/pubmed/37388906
http://dx.doi.org/10.1016/j.xgen.2023.100332

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