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Demonstration of the Early Cardiac Bioavailability of a Non-Specific Cell-Targeted Peptide Using Radionuclide-Based Imaging In Vivo

The cardiac bioavailability of peptide drugs that inhibit harmful intracellular protein–protein interactions in cardiovascular diseases remains a challenging task in drug development. This study investigates whether a non-specific cell-targeted peptide drug is available in a timely manner at its int...

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Detalles Bibliográficos
Autores principales: Settelmeier, Stephan, Varasteh, Zohreh, Staniszewska, Magdalena, Beerlage, Anna-Lena, Zarrad, Fadi, Fendler, Wolfgang P., Rischpler, Christoph, Notni, Johannes, Totzeck, Matthias, Herrmann, Ken, Rassaf, Tienush, Hendgen-Cotta, Ulrike B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300709/
https://www.ncbi.nlm.nih.gov/pubmed/37375771
http://dx.doi.org/10.3390/ph16060824