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Demonstration of the Early Cardiac Bioavailability of a Non-Specific Cell-Targeted Peptide Using Radionuclide-Based Imaging In Vivo
The cardiac bioavailability of peptide drugs that inhibit harmful intracellular protein–protein interactions in cardiovascular diseases remains a challenging task in drug development. This study investigates whether a non-specific cell-targeted peptide drug is available in a timely manner at its int...
Autores principales: | Settelmeier, Stephan, Varasteh, Zohreh, Staniszewska, Magdalena, Beerlage, Anna-Lena, Zarrad, Fadi, Fendler, Wolfgang P., Rischpler, Christoph, Notni, Johannes, Totzeck, Matthias, Herrmann, Ken, Rassaf, Tienush, Hendgen-Cotta, Ulrike B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300709/ https://www.ncbi.nlm.nih.gov/pubmed/37375771 http://dx.doi.org/10.3390/ph16060824 |
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