G-Quadruplexes Formation by the C9orf72 Nucleotide Repeat Expansion d(GGGGCC)(n) and Conformation Regulation by Fangchinoline

The G-quadruplex (GQ)-forming hexanucleotide repeat expansion (HRE) in the C9orf72 (C9) gene has been found to be the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) (collectively, C9ALS/FTD), implying the great significance of modulating C9-HRE GQ structur...

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Detalles Bibliográficos
Autores principales: Zhang, Yun, Huang, Junliu, Yu, Kainan, Cui, Xiaojie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300829/
https://www.ncbi.nlm.nih.gov/pubmed/37375224
http://dx.doi.org/10.3390/molecules28124671

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300829/
https://www.ncbi.nlm.nih.gov/pubmed/37375224
http://dx.doi.org/10.3390/molecules28124671

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