Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics

The blood-brain barrier (BBB), while being the gatekeeper of the central nervous system (CNS), is a bottleneck for the treatment of neurological diseases. Unfortunately, most of the biologicals do not reach their brain targets in sufficient quantities. The antibody targeting of receptor-mediated tra...

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Detalles Bibliográficos
Autores principales: Rué, Laura, Jaspers, Tom, Degors, Isabelle M. S., Noppen, Sam, Schols, Dominique, De Strooper, Bart, Dewilde, Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300862/
https://www.ncbi.nlm.nih.gov/pubmed/37376196
http://dx.doi.org/10.3390/pharmaceutics15061748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300862/
https://www.ncbi.nlm.nih.gov/pubmed/37376196
http://dx.doi.org/10.3390/pharmaceutics15061748

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