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Novel Human/Non-Human Primate Cross-Reactive Anti-Transferrin Receptor Nanobodies for Brain Delivery of Biologics

The blood-brain barrier (BBB), while being the gatekeeper of the central nervous system (CNS), is a bottleneck for the treatment of neurological diseases. Unfortunately, most of the biologicals do not reach their brain targets in sufficient quantities. The antibody targeting of receptor-mediated tra...

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Detalles Bibliográficos
Autores principales:	Rué, Laura, Jaspers, Tom, Degors, Isabelle M. S., Noppen, Sam, Schols, Dominique, De Strooper, Bart, Dewilde, Maarten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300862/ https://www.ncbi.nlm.nih.gov/pubmed/37376196 http://dx.doi.org/10.3390/pharmaceutics15061748

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