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Novel Chlorin e6-Curcumin Derivatives as a Potential Photosensitizer: Synthesis, Characterization, and Anticancer Activity

Novel series of chlorin e6-curcumin derivatives were designed and synthesized. All the synthesized compounds 16, 17, 18, and 19 were tested for their photodynamic treatment (PDT) efficacy against human pancreatic cancer cell lines: AsPC-1, MIA-PaCa-2, and PANC-1. The cellular uptake study was perfor...

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Detalles Bibliográficos
Autores principales: Thapa Magar, Til Bahadur, Lee, Jusuk, Lee, Ji Hoon, Jeon, Juhee, Gurung, Pallavi, Lim, Junmo, Kim, Yong-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300926/
https://www.ncbi.nlm.nih.gov/pubmed/37376026
http://dx.doi.org/10.3390/pharmaceutics15061577