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Characterization of Metabolic Correlations of Ursodeoxycholic Acid with Other Bile Acid Species through In Vitro Sequential Metabolism and Isomer-Focused Identification

As a first-line agent for cholestasis treatment in a clinic, ursodeoxycholic acid rectifies the perturbed bile acids (BAs) submetabolome in a holistic manner. Considering the endogenous distribution of ursodeoxycholic acid and extensive occurrences of isomeric metabolites, it is challenging to point...

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Detalles Bibliográficos
Autores principales: Li, Wei, Chen, Wei, Niu, Xiaoya, Zhao, Chen, Tu, Pengfei, Li, Jun, Liu, Wenjing, Song, Yuelin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300935/
https://www.ncbi.nlm.nih.gov/pubmed/37375356
http://dx.doi.org/10.3390/molecules28124801