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Characterization of Metabolic Correlations of Ursodeoxycholic Acid with Other Bile Acid Species through In Vitro Sequential Metabolism and Isomer-Focused Identification
As a first-line agent for cholestasis treatment in a clinic, ursodeoxycholic acid rectifies the perturbed bile acids (BAs) submetabolome in a holistic manner. Considering the endogenous distribution of ursodeoxycholic acid and extensive occurrences of isomeric metabolites, it is challenging to point...
Autores principales: | Li, Wei, Chen, Wei, Niu, Xiaoya, Zhao, Chen, Tu, Pengfei, Li, Jun, Liu, Wenjing, Song, Yuelin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10300935/ https://www.ncbi.nlm.nih.gov/pubmed/37375356 http://dx.doi.org/10.3390/molecules28124801 |
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