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Holothurin A Inhibits RUNX1-Enhanced EMT in Metastasis Prostate Cancer via the Akt/JNK and P38 MAPK Signaling Pathway

Due to the challenge of prostate cancer (PCa) management, there has been a surge in efforts to identify more safe and effective compounds that can modulate the epithelial–mesenchymal transition (EMT) for driving metastasis. Holothurin A (HA), a triterpenoid saponin isolated from Holothuria scabra, h...

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Detalles Bibliográficos
Autores principales: Janta, Sirorat, Pranweerapaiboon, Kanta, Vivithanaporn, Pornpun, Plubrukarn, Anuchit, Chairoungdua, Arthit, Prasertsuksri, Prachayaporn, Apisawetakan, Somjai, Chaithirayanon, Kulathida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301049/
https://www.ncbi.nlm.nih.gov/pubmed/37367670
http://dx.doi.org/10.3390/md21060345