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Titanium-Mediated Reduction of Carboxamides to Amines with Borane–Ammonia

In this study, the successful titanium tetrachloride-catalyzed reduction of aldehydes, ketones, carboxylic acids, and nitriles with borane–ammonia was extended to the reduction (deoxygenation) of a variety of aromatic and aliphatic pri-, sec- and tert-carboxamides, by changing the stoichiometry of t...

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Detalles Bibliográficos
Autores principales: Ramachandran, P. Veeraraghavan, Alawaed, Abdulkhaliq A., Singh, Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301125/
https://www.ncbi.nlm.nih.gov/pubmed/37375131
http://dx.doi.org/10.3390/molecules28124575