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Peripheralization Strategies Applied to Morphinans and Implications for Improved Treatment of Pain

Opioids are considered the most effective analgesics for the treatment of moderate to severe acute and chronic pain. However, the inadequate benefit/risk ratio of currently available opioids, together with the current ‘opioid crisis’, warrant consideration on new opioid analgesic discovery strategie...

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Detalles Bibliográficos
Autores principales: Schmidhammer, Helmut, Al-Khrasani, Mahmoud, Fürst, Susanna, Spetea, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301144/
https://www.ncbi.nlm.nih.gov/pubmed/37375318
http://dx.doi.org/10.3390/molecules28124761