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Evidence of a New Crystalline Phase of Prednisolone Obtained from the Study of the Hydration–Dehydration Mechanisms of the Sesquihydrate

The dehydration of prednisolone sesquihydrate is studied and characterized by different physico-chemical analysis methods. The meticulous study of this dehydration led to the highlighting of a new solid form (form 3), metastable, never identified before. In a second step, the rehydration of anhydrou...

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Detalles Bibliográficos
Autores principales: Lemercier, Aurélien, Couvrat, Nicolas, Cartigny, Yohann, Sanselme, Morgane, Corvis, Yohann, Espeau, Philippe, Coquerel, Gérard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301155/
https://www.ncbi.nlm.nih.gov/pubmed/37376142
http://dx.doi.org/10.3390/pharmaceutics15061694