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A Phase 1 Two-Arm, Randomized, Double-Blind, Active-Controlled Study of Live, Oral Plasmid-Derived Adenovirus Type 4 and Type 7 Vaccines in Seronegative Adults

PXVX0047 is an investigational vaccine developed for active immunization to prevent febrile acute respiratory disease (ARD) caused by adenovirus serotypes 4 (Ad4) and 7 (Ad7). PXVX0047 consists of a modernized, plasmid-derived vaccine that was generated using a virus isolated from Wyeth Ad4 and Ad7...

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Detalles Bibliográficos
Autores principales: Beaty, Shannon, Collins, Natalie, Karasavvas, Nicos, Kuschner, Robert, Hang, Jun, Adhikari, Anima, Maljkovic Berry, Irina, Fung, Christian, Walls, Shannon, Betancourt, Elena, Mendy, Jason, Lock, Michael, Gierman, Emma, Bennett, Sean, Shabram, Paul, Warfield, Kelly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301169/
https://www.ncbi.nlm.nih.gov/pubmed/37376480
http://dx.doi.org/10.3390/vaccines11061091