Assisted Reductive Amination for Quantitation of Tryptophan, 5-Hydroxytryptophan, and Serotonin by Ultraperformance Liquid Chromatography Coupled with Tandem Mass Spectrometry

Herein, we used isotopic formaldehyde and sodium cyanoborohydride via reductive amination to label two methyl groups on primary amine to arrange the standards (h(2)-formaldehyde-modified) and internal standards (ISs, d(2)-formaldehyde-modified) of tryptophan and its metabolites, such as serotonin (5...

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Detalles Bibliográficos
Autores principales: Liang, Shih-Shin, Shen, Po-Tsun, Liang, Yu-Qing, Ke, Yi-Wen, Cheng, Chieh-Wen, Lin, Yi-Reng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301174/
https://www.ncbi.nlm.nih.gov/pubmed/37375135
http://dx.doi.org/10.3390/molecules28124580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301174/
https://www.ncbi.nlm.nih.gov/pubmed/37375135
http://dx.doi.org/10.3390/molecules28124580

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