Efficient Generation of Multiple Seamless Point Mutations Conferring Triazole Resistance in Aspergillus fumigatus

Aspergillus fumigatus is a common human fungal pathogen that can cause a range of diseases. Triazoles are used to treat A. fumigatus infections, but resistance is increasing due to mutations in genes such as cyp51A, hmg1 and overexpression of efflux pumps. Verifying the importance of these mutations...

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Detalles Bibliográficos
Autores principales: Handelman, Mariana, Osherov, Nir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301212/
https://www.ncbi.nlm.nih.gov/pubmed/37367580
http://dx.doi.org/10.3390/jof9060644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301212/
https://www.ncbi.nlm.nih.gov/pubmed/37367580
http://dx.doi.org/10.3390/jof9060644

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