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Dapagliflozin Mitigates Hypotension in Lipopolysaccharide-Induced Acute Inflammation Independent of Glycemia Level

Sodium-glucose cotransporter-2 (SGLT2) inhibitors have been suggested to have anti-inflammatory properties in diabetes. The goal of this study was to evaluate the role of the SGLT2 inhibitor dapagliflozin (DAPA) in the attenuation of lipopolysaccharide (LPS)-induced hypotension. Male Wistar albino r...

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Detalles Bibliográficos
Autores principales: Alanazi, Wael A., Alharbi, Turki, El-Nagar, Doaa M., Albogami, Abdullah M., Alswayyed, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301321/
https://www.ncbi.nlm.nih.gov/pubmed/37376131
http://dx.doi.org/10.3390/pharmaceutics15061683