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Design, Synthesis, and Anticancer Activity of Novel 3,6-Diunsaturated 2,5-Diketopiperazines

Based on the marine natural products piperafizine B, XR334, and our previously reported compound 4m, fourteen novel 3,6-diunsaturated 2,5-diketopiperazine (2,5-DKP) derivatives (1, 2, 4–6, 8–16), together with two known ones (3 and 7), were designed and synthesized as anticancer agents against the A...

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Detalles Bibliográficos
Autores principales: Li, Xiaolin, Xun, Tianrong, Xu, Huayan, Pang, Xiaoyan, Yang, Bin, Wang, Junfeng, Zhou, Xuefeng, Lin, Xiuping, Tan, Suiyi, Liu, Yonghong, Liao, Shengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301345/
https://www.ncbi.nlm.nih.gov/pubmed/37367651
http://dx.doi.org/10.3390/md21060325