Neutralizing and Enhancing Epitopes of the SARS-CoV-2 Receptor-Binding Domain (RBD) Identified by Nanobodies

Engineered nanobodies (VHs) to the SARS-CoV-2 receptor-binding domain (RBD) were generated using phage display technology. A recombinant Wuhan RBD served as bait in phage panning to fish out nanobody-displaying phages from a VH/V(H)H phage display library. Sixteen phage-infected E. coli clones produ...

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Detalles Bibliográficos
Autores principales: Kaewchim, Kanasap, Glab-ampai, Kittirat, Mahasongkram, Kodchakorn, Saenlom, Thanatsaran, Thepsawat, Watayagorn, Chulanetra, Monrat, Choowongkomon, Kiattawee, Sookrung, Nitat, Chaicumpa, Wanpen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301551/
https://www.ncbi.nlm.nih.gov/pubmed/37376552
http://dx.doi.org/10.3390/v15061252

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301551/
https://www.ncbi.nlm.nih.gov/pubmed/37376552
http://dx.doi.org/10.3390/v15061252

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