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Neutralizing and Enhancing Epitopes of the SARS-CoV-2 Receptor-Binding Domain (RBD) Identified by Nanobodies
Engineered nanobodies (VHs) to the SARS-CoV-2 receptor-binding domain (RBD) were generated using phage display technology. A recombinant Wuhan RBD served as bait in phage panning to fish out nanobody-displaying phages from a VH/V(H)H phage display library. Sixteen phage-infected E. coli clones produ...
Autores principales: | Kaewchim, Kanasap, Glab-ampai, Kittirat, Mahasongkram, Kodchakorn, Saenlom, Thanatsaran, Thepsawat, Watayagorn, Chulanetra, Monrat, Choowongkomon, Kiattawee, Sookrung, Nitat, Chaicumpa, Wanpen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301551/ https://www.ncbi.nlm.nih.gov/pubmed/37376552 http://dx.doi.org/10.3390/v15061252 |
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