Synthesis of Brominated Lactones Related to Mycalin A: Selective Antiproliferative Activity on Metastatic Melanoma Cells and Inhibition of the Cell Migration

Starting from D-xylonolactone and D-ribonolactone, several five-membered bromolactones, related to the C1–C5 portion of mycalin A lactone, have been synthesized. The bromination of D-ribonolactone with HBr/AcOH, without a subsequent transesterification step, has been studied for the first time, givi...

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Detalles Bibliográficos
Autores principales: Capasso, Domenica, Marino, Paola, Di Gaetano, Sonia, Borbone, Nicola, Terracciano, Monica, Trani, Roberta, Longo, Caterina, Piccialli, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301594/
https://www.ncbi.nlm.nih.gov/pubmed/37367674
http://dx.doi.org/10.3390/md21060349

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301594/
https://www.ncbi.nlm.nih.gov/pubmed/37367674
http://dx.doi.org/10.3390/md21060349

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