Cargando…

Synthesis of Brominated Lactones Related to Mycalin A: Selective Antiproliferative Activity on Metastatic Melanoma Cells and Inhibition of the Cell Migration

Starting from D-xylonolactone and D-ribonolactone, several five-membered bromolactones, related to the C1–C5 portion of mycalin A lactone, have been synthesized. The bromination of D-ribonolactone with HBr/AcOH, without a subsequent transesterification step, has been studied for the first time, givi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Capasso, Domenica, Marino, Paola, Di Gaetano, Sonia, Borbone, Nicola, Terracciano, Monica, Trani, Roberta, Longo, Caterina, Piccialli, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301594/ https://www.ncbi.nlm.nih.gov/pubmed/37367674 http://dx.doi.org/10.3390/md21060349

Ejemplares similares

Antiproliferative Activity of Mycalin A and Its Analogues on Human Skin Melanoma and Human Cervical Cancer Cells
por: Capasso, Domenica, et al.
Publicado: (2020)

Probing the DNA Reactivity and the Anticancer Properties of a Novel Tubercidin-Pt(II) Complex
por: D’Errico, Stefano, et al.
Publicado: (2020)

Phosphodiester Silybin Dimers Powerful Radical Scavengers: A Antiproliferative Activity on Different Cancer Cell Lines
por: Romanucci, Valeria, et al.
Publicado: (2022)

Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes
por: Riccardi, Claudia, et al.
Publicado: (2020)

Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin
por: Greco, Francesca, et al.
Publicado: (2022)

Antiproliferative Effect of Rottlerin on Sk-Mel-28 Melanoma Cells
por: Daveri, Elena, et al.
Publicado: (2015)

5-Amino-1-(2′,3′-O-isopropylidene-d-ribityl)-1H-imidazole-4-carboxamide: a crystal structure with Z′ = 4
por: Piccialli, Vincenzo, et al.
Publicado: (2017)

Studies toward the Synthesis of Smenamide A, an Antiproliferative Metabolite from Smenospongia aurea: Total Synthesis of ent-Smenamide A and 16-epi-Smenamide A
por: Caso, Alessia, et al.
Publicado: (2017)

A two-phase bromination process using tetraalkylammonium hydroxide for the practical synthesis of α-bromolactones from lactones
por: Yamamoto, Yuki, et al.
Publicado: (2021)

Nucleic Acids as Biotools at the Interface between Chemistry and Nanomedicine in the COVID-19 Era
por: Borbone, Nicola, et al.
Publicado: (2022)

Porous Silicon-Based Aptasensors: The Next Generation of Label-Free Devices for Health Monitoring
por: Terracciano, Monica, et al.
Publicado: (2019)

Sesquiterpene Lactones and Flavonoids from Psephellus pyrrhoblepharus with Antiproliferative Activity on Human Gynecological Cancer Cell Lines
por: Tastan, Pelin, et al.
Publicado: (2019)

3β,6α-Diacetoxy-5,9α-dihydroxy-5α-cholest-7-en-11-one
por: Piccialli, Vincenzo, et al.
Publicado: (2013)

(3R,3aR,6R,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diyl dibenzoate
por: Piccialli, Vincenzo, et al.
Publicado: (2013)

3β,6β-Diacetoxy-5,9α-dihydroxy-5α-cholest-7-en-11-one acetic acid 0.04-solvate
por: Piccialli, Vincenzo, et al.
Publicado: (2013)

Antiproliferative and cytotoxic effects of sesquiterpene lactones isolated from Ambrosia artemisiifolia on human adenocarcinoma and normal cell lines
por: Kovács, Balázs, et al.
Publicado: (2022)

Synthesis of cyclic N(1)-pentylinosine phosphate, a new structurally reduced cADPR analogue with calcium-mobilizing activity on PC12 cells
por: Mahal, Ahmed, et al.
Publicado: (2015)

Solid-Phase Synthesis of a New Diphosphate 5-Aminoimidazole-4-carboxamide Riboside (AICAR) Derivative and Studies toward Cyclic AICAR Diphosphate Ribose
por: D’Errico, Stefano, et al.
Publicado: (2011)

Synthesis of New Acadesine (AICA-riboside) Analogues Having Acyclic d-ribityl or 4-Hydroxybutyl Chains in Place of the Ribose
por: D’Errico, Stefano, et al.
Publicado: (2013)

The Anti-Proliferative Effect of L-Carnosine Correlates with a Decreased Expression of Hypoxia Inducible Factor 1 alpha in Human Colon Cancer Cells
por: Iovine, Barbara, et al.
Publicado: (2014)

Brominated Thiophenes as Precursors in the Preparation of Brominated and Arylated Anthraquinones
por: Thiemann, Thies, et al.
Publicado: (2009)

A Facile Synthesis of 5′-Fluoro-5′-deoxyacadesine (5′-F-AICAR): A Novel Non-phosphorylable AICAR Analogue
por: D’Errico, Stefano, et al.
Publicado: (2012)

Isolation of a Bis-Iodurated Tetra-THF as a Trace Product from the Oxidation of Squalene with RuO(4) and Its Double Ring Expansion to a Novel bis-THF-bis-THP Compound
por: Piccialli, Vincenzo, et al.
Publicado: (2011)

CD, UV, and In Silico Insights on the Effect of 1,3-Bis(1′-uracilyl)-2-propanone on Serum Albumin Structure
por: Greco, Francesca, et al.
Publicado: (2022)

Antiproliferative and Apoptotic Potential of Cyanidin-Based Anthocyanins on Melanoma Cells
por: Rugină, Dumitriţa, et al.
Publicado: (2017)

RGDechi-hCit: αvβ3 Selective Pro-Apoptotic Peptide as Potential Carrier for Drug Delivery into Melanoma Metastatic Cells
por: Capasso, Domenica, et al.
Publicado: (2014)

Synthesis of mixed-sequence oligonucleotides on mesoporous silicon: chemical strategies and material stability
por: Terracciano, Monica, et al.
Publicado: (2014)

New Linear Precursors of cIDPR Derivatives as Stable Analogs of cADPR: A Potent Second Messenger with Ca(2+)-Modulating Activity Isolated from Sea Urchin Eggs
por: D’Errico, Stefano, et al.
Publicado: (2019)

Nucleoside Analogs and Nucleoside Precursors as Drugs in the Fight against SARS-CoV-2 and Other Coronaviruses
por: Borbone, Nicola, et al.
Publicado: (2021)

Oxidation of Aldoses With Bromine
por: Isbell, Horace S.
Publicado: (1962)

Bromine as a Disinfectant
Publicado: (1891)

Treatment of Cancer by Bromine
Publicado: (1878)

Electrochemical Bromination of Glycals
por: Luo, Zhao-Xiang, et al.
Publicado: (2021)

Bromine-Lithia Water
por: Crother, T. D.
Publicado: (1890)

Bromine in Hospital Gangrene
por: Alley, Wm. B.
Publicado: (1863)

Directions for Using Bromine
por: Goldsmith, M.
Publicado: (1863)

Bromine and Its Compounds
por: Hollister, J. H.
Publicado: (1866)

In vitro antiproliferative and apoptotic effects of thiosemicarbazones based on (-)-camphene and R-(+)-limonene in human melanoma cells
por: Soares, Paula Roberta Otaviano, et al.
Publicado: (2023)

Quaternized chitosan promotes the antiproliferative effect of vemurafenib in melanoma cells by increasing cell permeability
por: Li, Min, et al.
Publicado: (2018)

Antiproliferative and pro-apoptotic activity of eugenol-related biphenyls on malignant melanoma cells
por: Pisano, Marina, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_4fa4s5uo4sher78hjlfgehc0ju