Precision Deuteration Using Cu-Catalyzed Transfer Hydrodeuteration to Access Small Molecules Deuterated at the Benzylic Position

[Image: see text] A highly regio- and chemoselective Cu-catalyzed aryl alkyne transfer hydrodeuteration to access a diverse scope of aryl alkanes precisely deuterated at the benzylic position is described. The reaction benefits from a high degree of regiocontrol in the alkyne hydrocupration step, le...

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Detalles Bibliográficos
Autores principales: Sloane, Samantha E., Vang, Zoua Pa, Nelson, Genevieve, Qi, Lihan, Sonstrom, Reilly E., Alansari, Isabella Y., Behlow, Kiera T., Pate, Brooks H., Neufeldt, Sharon R., Clark, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301681/
https://www.ncbi.nlm.nih.gov/pubmed/37388686
http://dx.doi.org/10.1021/jacsau.3c00053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301681/
https://www.ncbi.nlm.nih.gov/pubmed/37388686
http://dx.doi.org/10.1021/jacsau.3c00053

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