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Conquering the Synthesis and Functionalization of Bicyclo[1.1.1]pentanes
[Image: see text] Bicyclo[1.1.1]pentanes (BCPs) have become established as attractive bioisosteres for para-substituted benzene rings in drug design. Conferring various beneficial properties compared with their aromatic “parents,” BCPs featuring a wide array of bridgehead substituents can now be acc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301682/ https://www.ncbi.nlm.nih.gov/pubmed/37388694 http://dx.doi.org/10.1021/jacsau.3c00014 |