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Molecular determinants of TRPM8 function: key clues for a cool modulation

Cold thermoreceptor neurons detect temperature drops with highly sensitive molecular machinery concentrated in their peripheral free nerve endings. The main molecular entity responsible for cold transduction in these neurons is the thermo-TRP channel TRPM8. Cold, cooling compounds such as menthol, v...

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Detalles Bibliográficos
Autores principales: Pertusa, María, Solorza, Jocelyn, Madrid, Rodolfo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301734/
https://www.ncbi.nlm.nih.gov/pubmed/37388453
http://dx.doi.org/10.3389/fphar.2023.1213337