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Inappropriate activation of the renin-angiotensin system improves cardiac tolerance to ischemia/reperfusion injury in rats with late angiotensin II-dependent hypertension

The aim of the study was to clarify the role of the interplay between hypertension and the renin-angiotensin system (RAS) in the pathophysiology of myocardial ischemia/reperfusion (I/R) injury. We hypothesized that in the late phase of hypertension with already developed signs of end-organ damage, i...

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Detalles Bibliográficos
Autores principales: Husková, Zuzana, Kikerlová, Soňa, Miklovič, Matúš, Kala, Petr, Papoušek, František, Neckář, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301744/
https://www.ncbi.nlm.nih.gov/pubmed/37389123
http://dx.doi.org/10.3389/fphys.2023.1151308