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Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid–Polymer Hybrid Nanocarriers

The feasibility of using lipid–polymer hybrid (LPH) nanocarriers as a potential platform for the intranasal delivery of ziprasidone (ZP), a second-generation antipsychotic, was explored. Different ZP-loaded LPH composed of a PLGA core and cholesterol-lecithin lipid coat were prepared using a single...

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Detalles Bibliográficos
Autores principales: Abo El-Enin, Hadel A., Tulbah, Alaa S., Darwish, Hany W., Salama, Rania, Naguib, Ibrahim A., Yassin, Heba A., Abdel-Bar, Hend Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301809/
https://www.ncbi.nlm.nih.gov/pubmed/37375832
http://dx.doi.org/10.3390/ph16060886