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Evaluation of Brain Targeting and Antipsychotic Activity of Nasally Administrated Ziprasidone Lipid–Polymer Hybrid Nanocarriers
The feasibility of using lipid–polymer hybrid (LPH) nanocarriers as a potential platform for the intranasal delivery of ziprasidone (ZP), a second-generation antipsychotic, was explored. Different ZP-loaded LPH composed of a PLGA core and cholesterol-lecithin lipid coat were prepared using a single...
Autores principales: | Abo El-Enin, Hadel A., Tulbah, Alaa S., Darwish, Hany W., Salama, Rania, Naguib, Ibrahim A., Yassin, Heba A., Abdel-Bar, Hend Mohamed |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301809/ https://www.ncbi.nlm.nih.gov/pubmed/37375832 http://dx.doi.org/10.3390/ph16060886 |
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