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Generation of a SARS-CoV-2 Reverse Genetics System and Novel Human Lung Cell Lines That Exhibit High Virus-Induced Cytopathology

The global COVID-19 pandemic continues with continued cases worldwide and the emergence of new SARS-CoV-2 variants. In our study, we have developed novel tools with applications for screening antivirals, identifying virus–host dependencies, and characterizing viral variants. Using reverse genetics,...

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Detalles Bibliográficos
Autores principales: Khan, Juveriya Qamar, Rohamare, Megha, Rajamanickam, Karthic, Bhanumathy, Kalpana K., Lew, Jocelyne, Kumar, Anil, Falzarano, Darryl, Vizeacoumar, Franco J., Wilson, Joyce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301824/
https://www.ncbi.nlm.nih.gov/pubmed/37376581
http://dx.doi.org/10.3390/v15061281