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Intra-articular injection of secretome, derived from umbilical cord mesenchymal stem cell, enhances the regeneration process of cartilage in early-stage osteo-arthritis: an animal study

BACKGROUND AND PURPOSE: Mesenchymal stem cells (MSCs), both endogenous and exogenous, enhance chondrocyte proliferation by stimulating collagen type II. Secretome, an MSC derivate, has shown to also provide this mechanism through a paracrine effect. We aimed to evaluate the use of secretome and MSC...

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Detalles Bibliográficos
Autores principales: LUBIS, Andri Maruli Tua, APRIANTO, Petrus, PAWITAN, Jeanne Adiwinata, PRIOSOERYANTO, Bambang Pontjo, DEWI, Tri Isyani Tungga, KAMAL, Achmad Fauzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medical Journals Sweden, on behalf of the Nordic Orthopedic Federation 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301849/
https://www.ncbi.nlm.nih.gov/pubmed/37377012
http://dx.doi.org/10.2340/17453674.2023.12359